I had this idea for short, since both you and seth mcfarlane love to make fun of the kool-aid man. But this is more robot chicken style.
Scenario: Outside some appartment block, you hear a couple fighting inside. Eventually they start saying "Oh Yeah? - Yeah!! -OH YEAH?? - YEAH!!..." Then you'd see how the kool-aid man gets to the scene so fast (rope, helicopter, running feal fast). He attempts to jump through the wall but fails and his jug springs a leak and he starts yelling "Oh NO!"

And for my additional two cents, if you would make a clip from a video game, it would have to be GTA san andreas or IV.
Switch.
Aim High...Headshots!